Peter - I totally agree with you it generally takes me about a week of much listening to determine the real merits or not of a change.
But in respect of clocks on the USB interface I would have to say that improved clocks is a total no brainer regardless of XX settings (to these ears at least) - the reduction in glare and hash is immediately obvious OK extended listening is always needed but I just cannot believe that I would ever change my mind on that particular one (but hey I have been wrong before). Of course noise profile is all - and each system potentially is different so I can only comment on what I hear in my system and in Nicks.
But there again I remember installing the PCie card with the banks of capacitors and that made a big improvement only to be totally negated when you changed XX for W8 mmmm.
Your mention of XX settings is very relevant. Since moving to W8 XX settings became much less important in my system. In my system with the Paul Pang clock in place XX settings now have a bigger effect. Also at Nicks yesterday with improved USB clocks XX settings become much more important. Nick was able to "tune" the sound of the system using XX settings.